Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer’s Disease

Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one of the earliest sites of pathology and degeneratio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurobiol Dis
Prif Awduron: Evans, Andrew K., Ardestani, Pooneh, Yi, Bitna, Park, Heui Hye, Lam, Rachel, Shamloo, Mehrdad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686098/
https://ncbi.nlm.nih.gov/pubmed/32971233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105089
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