The genomic regulatory elements for estrogen receptor alpha transactivation-function-1 regulated genes

Estrogen receptor alpha (ERα) is a ligand-dependent transcription regulator, containing two transactivation functional domains, AF-1 and AF-2. The selective estrogen receptor modulators (SERMs), including 4-hydroxytamoxifen (4OHT), activate AF-1 preferentially rather than AF-2. However, it is unclea...

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Publicado en:FASEB J
Autores principales: Arao, Yukitomo, Hamilton, Katherine J, Grimm, Sara A, Korach, Kenneth S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7686083/
https://ncbi.nlm.nih.gov/pubmed/33064339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001435R
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