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N-terminal transactivation function, AF-1, of estrogen receptor alpha controls obesity through enhancement of energy expenditure

OBJECTIVE: Studies using the estrogen receptor alpha (ERα) knock-out (αERKO) mice have demonstrated that ERα plays a crucial role in various estrogen-mediated metabolic regulations. ERα is a ligand dependent transcription regulator and its activity is regulated by estrogenic compounds. ERα consists...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Arao, Yukitomo, Hamilton, Katherine J., Lierz, Sydney L., Korach, Kenneth S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308972/
https://ncbi.nlm.nih.gov/pubmed/30287090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.09.006
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