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The Transactivating Function 2 (AF-2) of Estrogen Receptor (ER) α is Indispensable for ERα-mediated Physiological Responses and AF-1 Activity

Estrogen has various physiological functions and the estrogen receptor (ER) is a key regulator of those functions. ERα is a ligand-dependent transcription factor and that activity is mediated by the transactivating function-1 (AF-1) in the N-terminal domain and transactivating function-2 (AF-2) in t...

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Pubblicato in:Open J Endocr Metab Dis
Autori principali: Arao, Yukitomo, Hamilton, Katherine J., Korach, Kenneth S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177219/
https://ncbi.nlm.nih.gov/pubmed/30310730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4236/ojemd.2013.34A2002
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