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The Domino Effect Triggered by the Tethered Ligand of the Protease Activated Receptors
Protease activated receptors (PARs) are G-protein coupled receptors (GPCRs) that have a unique activation mechanism. Unlike other GPCRs that can be activated by free ligands, under physiological conditions, PARs are activated by the tethered ligand, which is a part of their N-terminus that is unmask...
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| Veröffentlicht in: | Thromb Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7686079/ https://ncbi.nlm.nih.gov/pubmed/32853981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2020.08.004 |
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