The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering

T lymphocytes are important mediators of adoptive immunity but the mechanism of T cell receptor (TCR) triggering remains uncertain. The interspatial distance between engaged T cells and antigen-presenting cells (APCs) is believed to be important for topological rearrangement of membrane tyrosine pho...

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Publicado en:Front Immunol
Autores principales: Chen, Bing-Mae, Al-Aghbar, Mohammad Ameen, Lee, Chien-Hsin, Chang, Tien-Ching, Su, Yu-Cheng, Li, Ya-Chen, Chang, Shih-En, Chen, Chin-Chuan, Chung, Tsai-Hua, Liao, Yuan-Chun, Lee, Chau-Hwang, Roffler, Steve R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502409/
https://ncbi.nlm.nih.gov/pubmed/28740495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00793
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