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Complement factor C4a does not activate protease‐activated receptor 1 (PAR1) or PAR4 on human platelets
BACKGROUND: Protease‐activated receptor (PAR) 1 and PAR4 are key thrombin signal mediators for human platelet activation and aggregation in response to vascular injury. They are primarily activated by thrombin cleavage of the N‐terminus to expose a tethered ligand. In addition to the canonical activ...
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| Publicado no: | Res Pract Thromb Haemost |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7845074/ https://ncbi.nlm.nih.gov/pubmed/33537534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12459 |
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