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Platelet Specific Promoters Are Insufficient to Express Protease Activated Receptor 1 (PAR1) Transgene in Mouse Platelets

The in vivo study of protease activated receptors (PARs) in platelets is complicated due to species specific expression profiles. Human platelets express PAR1 and PAR4 whereas mouse platelets express PAR3 and PAR4. Further, PAR subtypes interact with one another to influence activation and signaling...

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Detalhes bibliográficos
Main Authors: Arachiche, Amal, de la Fuente, María, Nieman, Marvin T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022678/
https://ncbi.nlm.nih.gov/pubmed/24830314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097724
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