Platelet Specific Promoters Are Insufficient to Express Protease Activated Receptor 1 (PAR1) Transgene in Mouse Platelets

The in vivo study of protease activated receptors (PARs) in platelets is complicated due to species specific expression profiles. Human platelets express PAR1 and PAR4 whereas mouse platelets express PAR3 and PAR4. Further, PAR subtypes interact with one another to influence activation and signaling...

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Bibliographic Details
Main Authors: Arachiche, Amal, de la Fuente, María, Nieman, Marvin T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022678/
https://ncbi.nlm.nih.gov/pubmed/24830314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097724
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