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Protease-activated receptors in hemostasis
Protease signaling in cells elicits multiple physiologically important responses via protease-activated receptors (PARs). There are 4 members of this family of G-protein–coupled receptors (PAR1-4). PARs are activated by proteolysis of the N terminus to reveal a tethered ligand. The rate-limiting ste...
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| Udgivet i: | Blood |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946198/ https://ncbi.nlm.nih.gov/pubmed/27127302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-11-636472 |
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