Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes

By restoring glucose-regulated insulin secretion, glucagon-like peptide-1–based (GLP-1–based) therapies are becoming increasingly important in diabetes care. Normally, the incretins GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) jointly maintain normal blood glucose levels by stimulati...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Invest
Egile Nagusiak: Oduori, Okechi S., Murao, Naoya, Shimomura, Kenju, Takahashi, Harumi, Zhang, Quan, Dou, Haiqiang, Sakai, Shihomi, Minami, Kohtaro, Chanclon, Belen, Guida, Claudia, Kothegala, Lakshmi, Tolö, Johan, Maejima, Yuko, Yokoi, Norihide, Minami, Yasuhiro, Miki, Takashi, Rorsman, Patrik, Seino, Susumu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685756/
https://ncbi.nlm.nih.gov/pubmed/33196462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140046
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