Gs/Gq signaling switch in β cells defines incretin effectiveness in diabetes

By restoring glucose-regulated insulin secretion, glucagon-like peptide-1–based (GLP-1–based) therapies are becoming increasingly important in diabetes care. Normally, the incretins GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) jointly maintain normal blood glucose levels by stimulati...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Clin Invest
Κύριοι συγγραφείς: Oduori, Okechi S., Murao, Naoya, Shimomura, Kenju, Takahashi, Harumi, Zhang, Quan, Dou, Haiqiang, Sakai, Shihomi, Minami, Kohtaro, Chanclon, Belen, Guida, Claudia, Kothegala, Lakshmi, Tolö, Johan, Maejima, Yuko, Yokoi, Norihide, Minami, Yasuhiro, Miki, Takashi, Rorsman, Patrik, Seino, Susumu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2020
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7685756/
https://ncbi.nlm.nih.gov/pubmed/33196462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI140046
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