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Selective Pd-Catalyzed Monoarylation of Small Primary Alkyl Amines through Backbone-Modification in Ylide-Functionalized Phosphines (YPhos)

[Image: see text] Ylide-substituted phosphines have been shown to be excellent ligands for C–N coupling reactions under mild reaction conditions. Here we report studies on the impact of the steric demand of the substituent in the ylide-backbone on the catalytic activity. Two new YPhos ligands with b...

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Pubblicato in:J Org Chem
Autori principali: Rodstein, Ilja, Prendes, Daniel Sowa, Wickert, Leon, Paaßen, Maurice, Gessner, Viktoria H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2020
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7684579/
https://ncbi.nlm.nih.gov/pubmed/32907331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c01771
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