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Coupling of Reformatsky Reagents with Aryl Chlorides Enabled by Ylide‐Functionalized Phosphine Ligands

The coupling of aryl chlorides with Reformatsky reagents is a desirable strategy for the construction of α‐aryl esters but has so far been substantially limited in the substrate scope due to many challenges posed by various possible side reactions. This limitation has now been overcome by the tailor...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Hu, Zhiyong, Wei, Xiao‐Jing, Handelmann, Jens, Seitz, Ann‐Katrin, Rodstein, Ilja, Gessner, Viktoria H., Gooßen, Lukas J.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7986804/
https://ncbi.nlm.nih.gov/pubmed/33427381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202016048
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