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The regulatory function of the AAA4 ATPase domain of cytoplasmic dynein

Cytoplasmic dynein is the primary motor for microtubule minus-end-directed transport and is indispensable to eukaryotic cells. Although each motor domain of dynein contains three active AAA+ ATPases (AAA1, 3, and 4), only the functions of AAA1 and 3 are known. Here, we use single-molecule fluorescen...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Xinglei, Rao, Lu, Gennerich, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683685/
https://ncbi.nlm.nih.gov/pubmed/33230227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19477-3
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