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The regulatory function of the AAA4 ATPase domain of cytoplasmic dynein

Cytoplasmic dynein is the primary motor for microtubule minus-end-directed transport and is indispensable to eukaryotic cells. Although each motor domain of dynein contains three active AAA+ ATPases (AAA1, 3, and 4), only the functions of AAA1 and 3 are known. Here, we use single-molecule fluorescen...

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Pubblicato in:Nat Commun
Autori principali: Liu, Xinglei, Rao, Lu, Gennerich, Arne
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683685/
https://ncbi.nlm.nih.gov/pubmed/33230227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19477-3
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