Загрузка...

Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies

Longitudinal preclinical and clinical studies suggest that Aβ drives neurite and synapse degeneration through an array of tau-dependent and independent mechanisms. The intracellular signaling networks regulated by the p75 neurotrophin receptor (p75(NTR)) substantially overlap with those linked to Aβ...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Yang, Tao, Tran, Kevin C., Zeng, Anne Y., Massa, Stephen M., Longo, Frank M.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683564/
https://ncbi.nlm.nih.gov/pubmed/33230162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77210-y
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!