Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus

Autoimmune diseases, such as systemic lupus erythematosus, are characterized by excessive inflammation in response to self-antigens. Loss of appropriate immunoregulatory mechanisms contribute to disease exacerbation. We previously showed the suppressive effect of vancomycin treatment during the “act...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Mu, Qinghui, Edwards, Michael R., Swartwout, Brianna K., Cabana Puig, Xavier, Mao, Jiangdi, Zhu, Jing, Grieco, Joe, Cecere, Thomas E., Prakash, Meeta, Reilly, Christopher M., Puglisi, Christopher, Bachali, Prathyusha, Grammer, Amrie C., Lipsky, Peter E., Luo, Xin M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683516/
https://ncbi.nlm.nih.gov/pubmed/33240280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.593353
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