Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus

Autoimmune diseases, such as systemic lupus erythematosus, are characterized by excessive inflammation in response to self-antigens. Loss of appropriate immunoregulatory mechanisms contribute to disease exacerbation. We previously showed the suppressive effect of vancomycin treatment during the “act...

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Gepubliceerd in:Front Immunol
Hoofdauteurs: Mu, Qinghui, Edwards, Michael R., Swartwout, Brianna K., Cabana Puig, Xavier, Mao, Jiangdi, Zhu, Jing, Grieco, Joe, Cecere, Thomas E., Prakash, Meeta, Reilly, Christopher M., Puglisi, Christopher, Bachali, Prathyusha, Grammer, Amrie C., Lipsky, Peter E., Luo, Xin M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683516/
https://ncbi.nlm.nih.gov/pubmed/33240280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.593353
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