Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus

Autoimmune diseases, such as systemic lupus erythematosus, are characterized by excessive inflammation in response to self-antigens. Loss of appropriate immunoregulatory mechanisms contribute to disease exacerbation. We previously showed the suppressive effect of vancomycin treatment during the “act...

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Vydáno v:Front Immunol
Hlavní autoři: Mu, Qinghui, Edwards, Michael R., Swartwout, Brianna K., Cabana Puig, Xavier, Mao, Jiangdi, Zhu, Jing, Grieco, Joe, Cecere, Thomas E., Prakash, Meeta, Reilly, Christopher M., Puglisi, Christopher, Bachali, Prathyusha, Grammer, Amrie C., Lipsky, Peter E., Luo, Xin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683516/
https://ncbi.nlm.nih.gov/pubmed/33240280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.593353
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