Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus

Autoimmune diseases, such as systemic lupus erythematosus, are characterized by excessive inflammation in response to self-antigens. Loss of appropriate immunoregulatory mechanisms contribute to disease exacerbation. We previously showed the suppressive effect of vancomycin treatment during the “act...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Mu, Qinghui, Edwards, Michael R., Swartwout, Brianna K., Cabana Puig, Xavier, Mao, Jiangdi, Zhu, Jing, Grieco, Joe, Cecere, Thomas E., Prakash, Meeta, Reilly, Christopher M., Puglisi, Christopher, Bachali, Prathyusha, Grammer, Amrie C., Lipsky, Peter E., Luo, Xin M.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683516/
https://ncbi.nlm.nih.gov/pubmed/33240280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.593353
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