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Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Gene expression signatures can stratify patients with heterogeneous diseases, such as systemic lupus erythematosus (SLE), yet understanding the contributions of ancestral background to this heterogeneity is not well understood. We hypothesized that ancestry would significantly influence gene express...

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Bibliografske podrobnosti
izdano v:JCI Insight
Main Authors: Catalina, Michelle D., Bachali, Prathyusha, Yeo, Anthony E., Geraci, Nicholas S., Petri, Michelle A., Grammer, Amrie C., Lipsky, Peter E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455079/
https://ncbi.nlm.nih.gov/pubmed/32759501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140380
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