Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Gene expression signatures can stratify patients with heterogeneous diseases, such as systemic lupus erythematosus (SLE), yet understanding the contributions of ancestral background to this heterogeneity is not well understood. We hypothesized that ancestry would significantly influence gene express...

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Bibliografische gegevens
Gepubliceerd in:JCI Insight
Hoofdauteurs: Catalina, Michelle D., Bachali, Prathyusha, Yeo, Anthony E., Geraci, Nicholas S., Petri, Michelle A., Grammer, Amrie C., Lipsky, Peter E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455079/
https://ncbi.nlm.nih.gov/pubmed/32759501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140380
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