Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Gene expression signatures can stratify patients with heterogeneous diseases, such as systemic lupus erythematosus (SLE), yet understanding the contributions of ancestral background to this heterogeneity is not well understood. We hypothesized that ancestry would significantly influence gene express...

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Publicat a:JCI Insight
Autors principals: Catalina, Michelle D., Bachali, Prathyusha, Yeo, Anthony E., Geraci, Nicholas S., Petri, Michelle A., Grammer, Amrie C., Lipsky, Peter E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455079/
https://ncbi.nlm.nih.gov/pubmed/32759501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140380
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