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Patient ancestry significantly contributes to molecular heterogeneity of systemic lupus erythematosus

Gene expression signatures can stratify patients with heterogeneous diseases, such as systemic lupus erythematosus (SLE), yet understanding the contributions of ancestral background to this heterogeneity is not well understood. We hypothesized that ancestry would significantly influence gene express...

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Publicado en:JCI Insight
Autores principales: Catalina, Michelle D., Bachali, Prathyusha, Yeo, Anthony E., Geraci, Nicholas S., Petri, Michelle A., Grammer, Amrie C., Lipsky, Peter E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7455079/
https://ncbi.nlm.nih.gov/pubmed/32759501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140380
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