Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering

Lentiviral vectors (LVs) are increasingly employed in gene and cell therapy. Standard laboratory production of LVs is not easily scalable, and research-grade LVs often contain contaminants that can interfere with downstream applications. Moreover, purified LV production pipelines have been developed...

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Foilsithe in:Mol Ther Methods Clin Dev
Main Authors: Soldi, Monica, Sergi Sergi, Lucia, Unali, Giulia, Kerzel, Thomas, Cuccovillo, Ivan, Capasso, Paola, Annoni, Andrea, Biffi, Mauro, Rancoita, Paola Maria Vittoria, Cantore, Alessio, Lombardo, Angelo, Naldini, Luigi, Squadrito, Mario Leonardo, Kajaste-Rudnitski, Anna
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2020
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7683235/
https://ncbi.nlm.nih.gov/pubmed/33294490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.10.009
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