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Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues

Sensorineural hearing loss is one of the most common disabilities worldwide. Such prevalence necessitates effective tools for studying the molecular workings of cochlear cells. One prominent and effective vector for expressing genes of interest in research models is adeno-associated virus (AAV). How...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Casey, Graham, Askew, Charles, Brimble, Mark A., Samulski, R. Jude, Davidoff, Andrew M., Li, Chengwen, Walters, Bradley J.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682903/
https://ncbi.nlm.nih.gov/pubmed/33227033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242599
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