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Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues

Sensorineural hearing loss is one of the most common disabilities worldwide. Such prevalence necessitates effective tools for studying the molecular workings of cochlear cells. One prominent and effective vector for expressing genes of interest in research models is adeno-associated virus (AAV). How...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Casey, Graham, Askew, Charles, Brimble, Mark A., Samulski, R. Jude, Davidoff, Andrew M., Li, Chengwen, Walters, Bradley J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682903/
https://ncbi.nlm.nih.gov/pubmed/33227033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242599
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