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Using B cell receptor lineage structures to predict affinity
We are frequently faced with a large collection of antibodies, and want to select those with highest affinity for their cognate antigen. When developing a first-line therapeutic for a novel pathogen, for instance, we might look for such antibodies in patients that have recovered. There exist effecti...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682889/ https://ncbi.nlm.nih.gov/pubmed/33175831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008391 |
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