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Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data

The collection of immunoglobulin genes in an individual’s germline, which gives rise to B cell receptors via recombination, is known to vary significantly across individuals. In humans, for example, each individual has only a fraction of the several hundred known V alleles. Furthermore, the currentl...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ralph, Duncan K., Matsen, Frederick A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675132/
https://ncbi.nlm.nih.gov/pubmed/31329576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007133
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