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Likelihood-Based Inference of B Cell Clonal Families

The human immune system depends on a highly diverse collection of antibody-making B cells. B cell receptor sequence diversity is generated by a random recombination process called “rearrangement” forming progenitor B cells, then a Darwinian process of lineage diversification and selection called “af...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ralph, Duncan K., Matsen, Frederick A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066976/
https://ncbi.nlm.nih.gov/pubmed/27749910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005086
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