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Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data
The collection of immunoglobulin genes in an individual’s germline, which gives rise to B cell receptors via recombination, is known to vary significantly across individuals. In humans, for example, each individual has only a fraction of the several hundred known V alleles. Furthermore, the currentl...
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| Veröffentlicht in: | PLoS Comput Biol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6675132/ https://ncbi.nlm.nih.gov/pubmed/31329576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007133 |
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