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Optogenetic regulation of embryo implantation in mice using photoactivatable CRISPR-Cas9
Embryo implantation is achieved upon successful interaction between a fertilized egg and receptive endometrium and is mediated by spatiotemporal expression of implantation-associated molecules including leukemia inhibitory factor (LIF). Here we demonstrate, in mice, that LIF knockdown via a photoact...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682590/ https://ncbi.nlm.nih.gov/pubmed/33139551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016850117 |
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