First-in-class humanized FSH blocking antibody targets bone and fat

Blocking the action of FSH genetically or pharmacologically in mice reduces body fat, lowers serum cholesterol, and increases bone mass, making an anti-FSH agent a potential therapeutic for three global epidemics: obesity, osteoporosis, and hypercholesterolemia. Here, we report the generation, struc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gera, Sakshi, Sant, Damini, Haider, Shozeb, Korkmaz, Funda, Kuo, Tan-Chun, Mathew, Mehr, Perez-Pena, Helena, Xie, Honglin, Chen, Hao, Batista, Rogerio, Ma, Kejun, Cheng, Zhen, Hadelia, Elina, Robinson, Cemre, Macdonald, Anne, Miyashita, Sari, Williams, Anthony, Jebian, Gregory, Miyashita, Hirotaka, Gumerova, Anisa, Ievleva, Kseniia, Smith, Pinar, He, Jiahuan, Ryu, Vitaly, DeMambro, Victoria, Quinn, Matthew A., Meseck, Marcia, Kim, Se-Min, Kumar, T. Rajendra, Iqbal, Jameel, New, Maria I., Lizneva, Daria, Rosen, Clifford J., Hsueh, Aaron J., Yuen, Tony, Zaidi, Mone
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7682550/
https://ncbi.nlm.nih.gov/pubmed/33127753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014588117
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados