Synthesis of Oligonucleotides containing the cis-Interstrand Crosslink Produced by Mitomycins in their Reaction with DNA.

Mitomycin C, (MC), an antitumor drug and decarbamoylmitomycin C, (DMC), a derivative of MC lacking the carbamoyl moiety, are DNA alkylating agents which can form DNA interstrand crosslinks (ICLs) between deoxyguanosine residues located on opposing DNA strands. MC forms primarily deoxyguanosine adduc...

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Detaylı Bibliyografya
Yayımlandı:Chemistry
Asıl Yazarlar: Aguilar, William, Zacarias, Owen, Romaine, Marian, Proni, Gloria, Petrovic, Ana G., Abzalimov, Rinat, Paz, Manuel M., Champeil, Elise
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7681910/
https://ncbi.nlm.nih.gov/pubmed/32574396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202002452
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