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Hoogsteen base pairs increase the susceptibility of double-stranded DNA to cytotoxic damage
As the Watson–Crick faces of nucleobases are protected in dsDNA, it is commonly assumed that deleterious alkylation damage to the Watson–Crick faces of nucleobases predominantly occurs when DNA becomes single-stranded during replication and transcription. However, damage to the Watson–Crick faces of...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7681010/ https://ncbi.nlm.nih.gov/pubmed/32913127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014530 |
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