Regulation of HCN2 Current by PI3K/Akt Signaling

It has long been known that heart rate is regulated by the autonomic nervous system. Recently, we demonstrated that the pacemaker current, I(f), is regulated by phosphoinositide 3-kinase (PI3K) signaling independently of the autonomic nervous system. Inhibition of PI3K in sinus node (SN) myocytes sh...

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Vydáno v:Front Physiol
Hlavní autoři: Lu, Zhongju, Wang, Hong Zhan, Gordon, Chris R., Ballou, Lisa M., Lin, Richard Z., Cohen, Ira S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680966/
https://ncbi.nlm.nih.gov/pubmed/33240105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.587040
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