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Regulation of heart rate and the pacemaker current by phosphoinositide 3-kinase signaling
Heart rate in physiological conditions is set by the sinoatrial node (SN), the primary cardiac pacing tissue. Phosphoinositide 3-kinase (PI3K) signaling is a major regulatory pathway in all normal cells, and its dysregulation is prominent in diabetes, cancer, and heart failure. Here, we show that in...
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| Publicado no: | J Gen Physiol |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6683667/ https://ncbi.nlm.nih.gov/pubmed/31217223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812293 |
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