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Restoration of defective L-type Ca(2+) current in cardiac myocytes of type 2 diabetic db/db mice by Akt and PKC-Ι
Diabetes is associated with increased risk of heart failure and development of a cardiomyopathy whose etiology is only partially understood. Ca(2+) entry through the voltage-dependent L-type Ca(2+) channel Ca(V)1.2 initiates the contractile cycle in cardiac myocytes. Decreased cardiac contractility...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615892/ https://ncbi.nlm.nih.gov/pubmed/21753738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e318228e68c |
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