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PKC-ε mediates multiple endothelin-1 actions on systolic Ca(2+) and contractility in ventricular myocytes
Endothelin-1 (ET-1) induces positive inotropy (enhanced contractility) in cardiac muscle, but establishing underlying cellular mechanisms has been controversial in part because of a growing number of signaling pathways and end effectors targeted by ET-1. Here we present evidence that ET-1 induces po...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3392465/ https://ncbi.nlm.nih.gov/pubmed/22699119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.06.024 |
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