Inhibition of miR-490-5p Promotes Human Adipose-Derived Stem Cells Chondrogenesis and Protects Chondrocytes via the PITPNM1/PI3K/AKT Axis

MicroRNAs (miRNAs) play a pivotal role in cartilage development and homeostasis in osteoarthritis (OA). While the fundamental roles of miRNAs in cartilage degeneration have been extensively studied, their effects on chondrogenic differentiation induced by human adipose-derived stem cells (hADSCs) an...

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Опубликовано в: :Front Cell Dev Biol
Главные авторы: Li, Hongyi, Zhao, Xiaoyi, Wen, Xingzhao, Zeng, Anyu, Mao, Guping, Lin, Ruifu, Hu, Shu, Liao, Weiming, Zhang, Zhiqi
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Cell and Developmental Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680841/
https://ncbi.nlm.nih.gov/pubmed/33240879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.573221
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