Inhibition of miR-490-5p Promotes Human Adipose-Derived Stem Cells Chondrogenesis and Protects Chondrocytes via the PITPNM1/PI3K/AKT Axis

MicroRNAs (miRNAs) play a pivotal role in cartilage development and homeostasis in osteoarthritis (OA). While the fundamental roles of miRNAs in cartilage degeneration have been extensively studied, their effects on chondrogenic differentiation induced by human adipose-derived stem cells (hADSCs) an...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Li, Hongyi, Zhao, Xiaoyi, Wen, Xingzhao, Zeng, Anyu, Mao, Guping, Lin, Ruifu, Hu, Shu, Liao, Weiming, Zhang, Zhiqi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680841/
https://ncbi.nlm.nih.gov/pubmed/33240879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.573221
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