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Function of the Chondrocyte PI-3 Kinase-Akt Signaling Pathway is Stimulus Dependent
OBJECTIVE: The PI-3 kinase-Akt pathway plays a role in cartilage anabolic as well as catabolic processes in response to activation by insulin-like growth factor-1 (IGF-1) and the pro-inflammatory cytokines interleukin-1β (IL-1β) and oncostatin M (OSM). The goal of this study was to determine how PI-...
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| Publicat a: | Osteoarthritis Cartilage |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4444401/ https://ncbi.nlm.nih.gov/pubmed/25659655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.01.014 |
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