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Function of the Chondrocyte PI-3 Kinase-Akt Signaling Pathway is Stimulus Dependent

OBJECTIVE: The PI-3 kinase-Akt pathway plays a role in cartilage anabolic as well as catabolic processes in response to activation by insulin-like growth factor-1 (IGF-1) and the pro-inflammatory cytokines interleukin-1β (IL-1β) and oncostatin M (OSM). The goal of this study was to determine how PI-...

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Bibliografski detalji
Izdano u:Osteoarthritis Cartilage
Glavni autori: Greene, Meredith A., Loeser, Richard F.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444401/
https://ncbi.nlm.nih.gov/pubmed/25659655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.01.014
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