Immune-mediated signaling in intestinal goblet cells via PI3-kinase- and AKT-dependent pathways

In the intestinal epithelium, activation of phosphatidylinositol 3-kinase (PI3-kinase)/AKT pathways, via growth factor-mediated signaling, has been shown to regulate cell proliferation and inhibit apoptosis. An immune-activated receptor critical for Th2 immune responses, IL-4Rα can also activate PI3...

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Detalhes bibliográficos
Main Authors: Wang, Mei-Lun, Keilbaugh, Sue A., Cash-Mason, Tanesha, He, Xi C., Li, Linheng, Wu, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Inflammation/Immunity/Mediators
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584832/
https://ncbi.nlm.nih.gov/pubmed/18832447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90430.2008
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