Inhibition of miR-490-5p Promotes Human Adipose-Derived Stem Cells Chondrogenesis and Protects Chondrocytes via the PITPNM1/PI3K/AKT Axis

MicroRNAs (miRNAs) play a pivotal role in cartilage development and homeostasis in osteoarthritis (OA). While the fundamental roles of miRNAs in cartilage degeneration have been extensively studied, their effects on chondrogenic differentiation induced by human adipose-derived stem cells (hADSCs) an...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Cell Dev Biol
Main Authors: Li, Hongyi, Zhao, Xiaoyi, Wen, Xingzhao, Zeng, Anyu, Mao, Guping, Lin, Ruifu, Hu, Shu, Liao, Weiming, Zhang, Zhiqi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Cell and Developmental Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680841/
https://ncbi.nlm.nih.gov/pubmed/33240879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.573221
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