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MicroRNA-455-3p promotes TGF-β signaling and inhibits osteoarthritis development by directly targeting PAK2

MicroRNAs (miRNAs, miR) play a key role in the pathogenesis of osteoarthritis (OA). Few studies have examined the regulatory role of P21-activated kinases (PAKs), a family of serine/threonine kinases, in OA. The aim of this study was to determine whether miR-455-3p can regulate cartilage degeneratio...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Exp Mol Med
मुख्य लेखकों: Hu, Shu, Zhao, Xiaoyi, Mao, Guping, Zhang, Ziji, Wen, Xingzhao, Zhang, Chengyun, Liao, Weiming, Zhang, Zhiqi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802609/
https://ncbi.nlm.nih.gov/pubmed/31586040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0322-3
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