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Synthesis of Enantiopure Triols from Racemic Baylis-Hillman Adducts Using a Diastereoselective Peroxidation Reaction

Using a chiral (−)-menthone auxiliary, enantiopure cyclic derivatives of Baylis-Hillman adducts were synthesized. A diastereoselective peroxidation reaction was used to introduce an oxygen atom and establish another stereocenter. The resulting products could be elaborated employing a one-flask reduc...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Zuckerman, Dylan S., Woerpel, K. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680403/
https://ncbi.nlm.nih.gov/pubmed/33141576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03439
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