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Synthesis of Sultam Scaffolds via Intramolecular Oxa-Michael and Diastereoselective Baylis—Hillman Reactions

[Image: see text] A divergent synthetic approach to new sultams utilizing intramolecular oxa-Michael and Baylis—Hillman reactions of readily prepared vinyl sulfonamides and suitably protected amino alcohols, is reported. A variety of seven- and eight-membered ring sultam scaffolds were synthesized u...

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Detalhes bibliográficos
Main Authors: Zhou, Aihua, Hanson, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742884/
https://ncbi.nlm.nih.gov/pubmed/18553974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8009072
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