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Synthesis of Enantiopure Triols from Racemic Baylis-Hillman Adducts Using a Diastereoselective Peroxidation Reaction

Using a chiral (−)-menthone auxiliary, enantiopure cyclic derivatives of Baylis-Hillman adducts were synthesized. A diastereoselective peroxidation reaction was used to introduce an oxygen atom and establish another stereocenter. The resulting products could be elaborated employing a one-flask reduc...

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Pubblicato in:Org Lett
Autori principali: Zuckerman, Dylan S., Woerpel, K. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680403/
https://ncbi.nlm.nih.gov/pubmed/33141576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.0c03439
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