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Delineation of metabolic responses of Npc1(−/−nih) mice lacking the cholesterol-esterifying enzyme SOAT2 to acute treatment with 2-hydroxypropyl-β-cyclodextrin
Lipids present in lipoproteins cleared from the circulation are processed sequentially by three major proteins within the late endosomal / lysosomal (E/L) compartment of all cells: lysosomal acid lipase (LAL), Niemann-Pick (NPC) C2 and NPC1. When all three of these proteins are functioning normally,...
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| Publicado no: | Steroids |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680374/ https://ncbi.nlm.nih.gov/pubmed/32890578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2020.108725 |
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