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K-Ras prenylation as a potential anticancer target
KRAS is one of the most commonly mutated oncogene and a negative predictive factor for a number of targeted therapies. Therefore, the development of targeting strategies against mutant KRAS is urgently needed. One potential strategy involves disruption of K-Ras membrane localization, which is necess...
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| Veröffentlicht in: | Cancer Metastasis Rev |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer US
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680335/ https://ncbi.nlm.nih.gov/pubmed/32524209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09902-w |
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