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K-Ras prenylation as a potential anticancer target

KRAS is one of the most commonly mutated oncogene and a negative predictive factor for a number of targeted therapies. Therefore, the development of targeting strategies against mutant KRAS is urgently needed. One potential strategy involves disruption of K-Ras membrane localization, which is necess...

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Bibliografische gegevens
Gepubliceerd in:Cancer Metastasis Rev
Hoofdauteurs: Baranyi, Marcell, Buday, László, Hegedűs, Balázs
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7680335/
https://ncbi.nlm.nih.gov/pubmed/32524209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09902-w
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