Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS

Approximately 30% of human cancers harbor a gain‐in‐function mutation in the RAS gene, resulting in constitutive activation of the RAS protein to stimulate downstream signaling, including the RAS‐mitogen activated protein kinase pathway that drives cancer cells to proliferate and metastasize. RAS‐dr...

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Vydáno v:MedComm (2020)
Hlavní autoři: Ward, Antonio B., Keeton, Adam B., Chen, Xi, Mattox, Tyler E., Coley, Alex B., Maxuitenko, Yulia Y., Buchsbaum, Donald J., Randall, Troy D., Zhou, Gang, Piazza, Gary A.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7567124/
https://ncbi.nlm.nih.gov/pubmed/33073260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mco2.10
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