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Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS
Approximately 30% of human cancers harbor a gain‐in‐function mutation in the RAS gene, resulting in constitutive activation of the RAS protein to stimulate downstream signaling, including the RAS‐mitogen activated protein kinase pathway that drives cancer cells to proliferate and metastasize. RAS‐dr...
Gardado en:
| Publicado en: | MedComm (2020) |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7567124/ https://ncbi.nlm.nih.gov/pubmed/33073260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mco2.10 |
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